Slater 3/26/01 Overview of GERD 10% of all Americans experience GERD Low mortality rate about 1 death per 100,000 persons Largely effects QOL: more than angina, menopause,untreated HTN, amiss(p) CHF GERD is defined as: Clinical or histological complaint resulting from gastric materials “refluxing” into the gullet This reflux causes a breakdown of the esophageal mucosa Pathophysiology of GERD Excessive reflux of gastric juices from the stomach to the gorge resulting in a breakdown of the defensive mech anisms of the esophagus. This breakdown leads to soreness and injury of the esophageal mucosa. Pathophysiology of GERD Causes of esophageal mucosa breakdown: impermanent/spontaneous LES relaxation Transient increase in intra-abdominal wardrobe Atonic LES LES tone can be caused by certain(a) foods, drugs, hormones, or other phys...If you want to get a intact essay, order it on our website: OrderEssay.net
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